Arthritis is common in people who tear knee ligaments

Former Dallas Texans player Christina Gordon (wearing brace) gave up club soccer after breaking her femur and tearing the ACL in both knees over a three-year span with the Texans. Dallas Morning News

By Jonathan Cluett MD, Verywell Health Updated June 27, 2019

Knee ligament injuries can be devastating injuries for a young athlete. Often causing prolonged absences from sports teams, significant rehabilitation, and interruption to a normal lifestyle, a torn knee ligament is an injury feared by most any young athlete.

However, most athletes, and their parents, coaches, and fans are worried about getting back to activity, not what might happen a decade or later. Unfortunately, the fact is, that the worst may be yet to come. New research is shedding light on how young athletes who have knee ligament injuries are more likely than not to develop arthritis of their joint within a decade of their injury.

Knee Ligament Injuries

There are four major knee ligaments, the two collateral ligaments on the sides of the knee, and the two cruciate ligaments that cross in the center of the knee. Most research investigating arthritis following knee ligament injuries has been on athletes who have torn their anterior cruciate ligament (ACL).

The ACL is an important ligament at preventing sensations of instability or ‘giving-out’ of the knee when performing a cutting or pivoting maneuver to change direction. ACL tears usually require surgical treatment, especially for athletes who participate in high-risk sports that require these sudden changes in direction as part of participation.

The surgery for a torn ACL is to make a new ligament, called a reconstruction, usually by taking tendon or ligament from somewhere else in the body. The success of surgery is generally good, although not perfect. Most athletes are able to return to sports activities after surgical reconstruction. However, the recovery is long and difficult, with athletes being out for a minimum of 6 months, and sometimes up to a year.

Arthritis of the Joint

Knee arthritis is a common problem, but most often associated with an elderly population. The most common type of arthritis is called osteoarthritis and is often referred to as wear-and-tear arthritis of the knee. When osteoarthritis occurs in the knee joint, the normally smooth, cushioning surface of the joint is worn away, leaving rough, exposed bone. The condition causes symptoms of pain, swelling, and deformity of the joint. Over time, the condition may worsen to a point that knee replacement may become an option.

As mentioned, knee arthritis is typically a condition of aging. Most people with arthritis are in their 60s or older. There are some risk factors for developing arthritis that can make the condition occur earlier in life. One of those risk factors is trauma to the knee, and a common type of traumatic injury is a knee ligament injury. Orthopedic surgeons have long known that people who tear their knee ligaments, including the ACL, are more likely to develop arthritis, but knowing how commonly and how soon this might occur was unclear.

A 2017 study found that about 75 percent of people who underwent ACL reconstructive surgery had arthritis findings on x-rays of their knee within 10-15 years of the time of surgery. This is a frightening finding, considering many ACL tears are treated in the teens and twenties of young athletes. These young people are then facing the prospect of managing knee arthritis as soon as in their 30s, a time when thoughts of arthritis are seldom on people’s minds. Risk of developing arthritis is especially high in young people who also damage the meniscus cartilage or articular cartilage, rather than those who have isolated ACL tears.

The exact cause of the arthritis is not completely understood, but it is likely a few different problems. First, the initial injury can damage joint cartilage in a way that cannot be seen. However, cartilage has little ability to repair itself, and the damage can become more apparent over time. Second, the mechanics of the knee may change after reconstructive surgery. While surgical techniques are being developed to better achieve normal knee mechanics after reconstruction, the benefit of these changes is not entirely clear.

How to Prevent It

It is very clear that the best way to prevent early arthritis is to prevent ACL injuries and other knee ligament injuries. This is a subject of a lot of research investigating methods to lower the likelihood of ACL injury. There are promising results from some of these methods, but no prevention program will eliminate all ACL tears. Furthermore, if you’ve read this far, it’s likely you or someone you care about already is managing a knee ligament tear.

Surgical reconstruction is felt to be a good method to prevent further damage to the joint. Every time the knee gives out, there is a risk of further cartilage damage in the joint. Therefore, many surgeons advise ACL surgery to prevent further damage in the knee. The benefit of bracing the knee is a subject of debate, but ACL braces have not been shown to improve results or prevent arthritis after having had ACL surgery.

Future Developments

As with many medical problems, there is a lot of investigation about how to improve the results for young athletes who injured knee ligaments. There are many who feel they have found ways to lower the likelihood of arthritis development, but the long-term effectiveness of these ideas has not been proven. Some investigations include:

Improving the mechanics of ACL reconstructive surgery

Some new surgical techniques have been developed to better replicate normal ACL anatomy or even repair the damaged ACL. Double-bundle ACL reconstruction and bridge enhanced ACL repair are some of these techniques, but if these are better than standard ACL reconstructive surgery is not known.

Changing the biology of the joint after injury

After an injury to a joint, such as a ligament tear, the body releases a variety of chemical signals within the joint. Altering the body’s response to ensure damage does not progress, and healing is optimal, is an area of investigation.

Preventing ligament injuries

Many investigations have been focused on understanding why some people tear their knee ligaments, and what can be done to prevent those injuries. Focusing on neuromuscular training, something called dynamic control of the extremity has been shown to help prevent knee ligament injury.

A Word From Verywell
Knee ligament injuries such as ACL tears are serious injuries that cause discomfort and time away from sports. Recovery from these injuries may require surgery and prolong rehab efforts. And if that’s not enough, the long term prognosis may not be good, with most people developing arthritis within a decade of injury. Future research is aimed at modifying the risk of developing arthritis and preventing ligament injuries from occurring at all.

Source Verywell Health

Preventing ACL Injuries and Improving Performance from the Osteoarthritis Action Alliance (OAAA)
The Osteoarthritis Action Alliance (OAAA) is supported, in part, by the Centers for Disease Control and Prevention. The Thurston Arthritis Research Center (TARC) at the University of North Carolina at Chapel Hill is the lead agency. Contents are solely the responsibility of the OAAA or TARC.
This publication is supported by Cooperative Agreement Number DP003828 from the Centers for Disease Control and Prevention. Its contents are solely the responsibility of the Arthritis Foundation and do not necessarily represent the official views of the Centers for Disease Control and Prevention.

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  Further reading

A novel approach to enhance ACL injury prevention programs, Gokeler A, Seil R, Kerkhoffs G, Verhagen E. J Exp Orthop. 2018 Jun 18;5(1):22. doi: 10.1186/s40634-018-0137-5. Full text

National Athletic Trainers’ Association Position Statement: Prevention of Anterior Cruciate Ligament Injury, Padua DA, DiStefano LJ, Hewett TE, Garrett WE, Marshall SW, Golden GM, Shultz SJ, Sigward SM. J Athl Train. 2018 Jan;53(1):5-19. doi: 10.4085/1062-6050-99-16. Epub 2018 Jan 9. Review. Full text

Prevalence of Radiographic Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction, With or Without Meniscectomy: An Evidence-Based Practice Article, Ruano JS, Sitler MR, Driban JB. J Athl Train. 2017 Jun 2;52(6):606-609. doi: 10.4085/1062-6050-51.2.14. Epub 2016 Mar 1. Full text

Anterior cruciate ligament reconstruction and knee osteoarthritis, Paschos NK. World J Orthop. 2017 Mar 18;8(3):212-217. doi: 10.5312/wjo.v8.i3.212. eCollection 2017 Mar 18. Full text

Which determinants predict tibiofemoral and patellofemoral osteoarthritis after anterior cruciate ligament injury? A systematic review, van Meer BL, Meuffels DE, van Eijsden WA, Verhaar JA, Bierma-Zeinstra SM, Reijman M. Br J Sports Med. 2015 Aug;49(15):975-83. doi: 10.1136/bjsports-2013-093258. Epub 2015 Mar 30. Review. Full text

Increased risk of osteoarthritis after anterior cruciate ligament reconstruction: a 14-year follow-up study of a randomized controlled trial, Barenius B, Ponzer S, Shalabi A, Bujak R, Norlén L, Eriksson K. Am J Sports Med. 2014 May;42(5):1049-57. doi: 10.1177/0363546514526139. Epub 2014 Mar 18.

Anterior cruciate ligament rupture and osteoarthritis progression, Wong JM, Khan T, Jayadev CS, Khan W, Johnstone D. Open Orthop J. 2012;6:295-300. doi: 10.2174/1874325001206010295. Epub 2012 Jul 27. Full text

Knee function and prevalence of knee osteoarthritis after anterior cruciate ligament reconstruction: a prospective study with 10 to 15 years of follow-up, Oiestad BE, Holm I, Aune AK, Gunderson R, Myklebust G, Engebretsen L, Fosdahl MA, Risberg MA. Am J Sports Med. 2010 Nov;38(11):2201-10. doi: 10.1177/0363546510373876. Epub 2010 Aug 16.

Prevention of physical training-related injuries recommendations for the military and other active populations based on expedited systematic reviews, Bullock SH, Jones BH, Gilchrist J, Marshall SW. Am J Prev Med. 2010 Jan;38(1 Suppl):S156-81. doi: 10.1016/j.amepre.2009.10.023. Review.

Prevalence of tibiofemoral osteoarthritis 15 years after nonoperative treatment of anterior cruciate ligament injury: a prospective cohort study, Neuman P, Englund M, Kostogiannis I, Fridén T, Roos H, Dahlberg LE. Am J Sports Med. 2008 Sep;36(9):1717-25. doi: 10.1177/0363546508316770. Epub 2008 May 15.

The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis, Lohmander LS, Englund PM, Dahl LL, Roos EM. Am J Sports Med. 2007 Oct;35(10):1756-69. Epub 2007 Aug 29. Review.

Also see
How Do Neuromuscular Training Programs Prevent ACL Tears? Verywell Health
Osteoarthritis Prevention: What You Can Do Arthritis Foundation
Osteoarthritis (OA) Prevention: Healthy Weight, Exercise, & More WebMD
If You Tear a Knee Ligament, Arthritis Is Likely to Follow in 10 Years The New York Times
The Lonely Road Back From a Very Public Injury The New York Times

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