Regenerative medicine

How to rewind the clock on arthritic cartilage

A new study in Aging Cell describes how a key protein, called Signal Transducer and Activator of Transcription 3 (STAT3), might turn back the clock on aging cartilage that leads to osteoarthritis. DNA. Creative Commons image by … READ MORE

‘Smart’ cartilage cells programmed to release drugs when stressed

New technology could lead to treatments for osteoarthritis. Researchers at Washington University School of Medicine in St. Louis have engineered cartilage cells to release an anti-inflammatory drug in response to stresses such cells … READ MORE

Regrowing cartilage in a damaged knee gets closer to fixing arthritis

A new ’tissue scaffold’ that holds the potential for a bioengineering breakthrough. UConn researchers Thanh Nguyen, left, and Yang Liu, with the tissue scaffold made out of a biodegradable polymer that they say holds … READ MORE

Researchers identify genes at play in people with osteoarthritis

After conducting the largest study on osteoarthritis in the world, researchers are now on track to develop a medicine that can slow it down. Researchers also identified the special risk factors that exist for women and for … READ MORE

Milestone in osteoarthritis research

Researchers found new genetic risk factors for osteoarthritis and identified novel drug targets. Their finding is a milestone towards the development of the first ever curative treatment for osteoarthritis. The study involved an … READ MORE

Lubricating arthritic knees with synthetic fluid may help tissue heal

Painful arthritic knees could be treated by injections of a lubricating fluid that mimics a natural version found in joints. Coloured X-ray of the knees of an 87-year old male patient with severe osteoarthritis. Dr P. Marazzi, Science … READ MORE

Researchers discover way to switch on and speed up tendon healing

Team at National University of Ireland Galway create implantable stimulator device which combines with body power to treat disease, damage and sports injury. This implantable device acts as mechanical support for damaged tendons and … READ MORE

New treatment to regain hand and arm function after spinal cord injury

Using physical therapy combined with a noninvasive method of stimulating nerve cells in the spinal cord, University of Washington researchers helped six Seattle area participants regain some hand and arm mobility. That increased … READ MORE

Regeneration race: Cartilage regrows faster in some joints than others

Thought regenerating tissue was just for salamanders? It turns out that humans can regenerate certain tissues faster than others too. A study authored by Duke researchers found that humans have the ability to regenerate cartilage in … READ MORE

Should I stop running if my knee hurts?

The most common site for pain in recreational runners is the knee. For some, especially older runners, the pain can be a symptom of osteoarthritis. But does running worsen knee pain and osteoarthritis? goodluz/Shutterstock Ewa M Roos, … READ MORE

Humans have salamander-like ability to regrow cartilage in joints

The process could be harnessed as a treatment for osteoarthritis. “We believe that an understanding of this ‘salamander-like’ regenerative capacity in humans, and the critically missing components of this regulatory circuit, … READ MORE

New wearable sensor for people with incomplete paraplegia

A new electromyography biofeedback device that is wearable and connects to novel smartphone games may offer people with incomplete paraplegia a more affordable, self-controllable therapy to enhance their recovery, according to a new … READ MORE

New evidence: Hip, knee steroid injections more dangerous than thought

A new study reveals that commonly given hip and knee steroid intra-articular injections may be harmful in some patients with at-risk conditions or may cause complications that are not well understood. These findings appear online in … READ MORE

Study tackles non-surgical treatment of knee osteoarthritis

This study is a head-to-head comparison of non-surgical treatment of knee osteoarthritis and total knee replacement surgery. Here is what they found. Florence Dressler illustration in Feminology 1902, page 607. Library of … READ MORE

Spinal stimulation enables three people with paraplegia to walk again

Combined with other recent studies, new evidence points to electrical stimulation as a promising treatment for paralysis. David, 28, who suffered a spinal cord injury, can walk (with a walker) for more than 1 kilometer with electrical … READ MORE

If your knee hurts, keep exercising, says expert

If you take up exercise later in life, as a treatment for joint or hip pain, you should expect a small, temporary increase in pain. But if you proceed sensibly, you will be rewarded with pain relief similar to that of a non-steroidal … READ MORE

Dancer’s path offers hope of walking for Orchard Park boy

Easton Jordan works on his walking steps with his physical therapist Elizabeth Bailey-Sands Clay at his home in Orchard Park NY. Mark Mulville, Buffalo News By Scott Scanlon, The Buffalo News June 9, 2017 Easton Jordan has seen Lauren … READ MORE

Non-surgical recovery of function: Not a fantasy

“Improved voluntary hand function occurred within a single session in every subject tested.” Dr. Reggie Edgerton, Director of UCLA Edgerton Lab, poses for a portrait in his lab on the campus in Los Angeles, California, March 16, … READ MORE

UCalgary scientists discover a new way to battle multiple sclerosis

Findings challenge conventional thinking about the root cause of MS. The Dr. Peter Stys lab within the Hotchkiss Brain Institute at the Cumming School of Medicine, University of Calgary, is equipped with highly specialized microscopes … READ MORE

Breakthrough for SF State kinesiologists studying metabolic protein

New technique could help improve treatment for diabetes and obesity. Assistant Professor of Kinesiology Jimmy Bagley and Irene Tobias, a postdoctoral researcher at CSU Fullerton, analyze muscle fibers. Andy Galpin CSU Fullerton By … READ MORE

The cure for osteoarthritis

A knee that is as good as new again, without major surgery or a prosthesis. That is something osteoarthritis patients can only dream of. But this will soon change, according to UT professor Marcel Karperien. If all goes well, the … READ MORE

Surprise finding could lead to new MS treatments

A discovery is providing hope of a new therapeutic target in Multiple Sclerosis (MS) patients that could one day be used to prevent the symptoms and progression of the disease. By removing a protein called calnexin in mice, … READ MORE

Scientists zero in on treatment for Charcot-Marie-Tooth disease

About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There is no … READ MORE

Health Canada approves Dysport to treat kids with cerebral palsy

Health Canada has approved Dysport (abobotulinumtoxinA) for the treatment of leg spasticity in children and teens ages 2 and older, including those with cerebral palsy. Six months ago, 13-year-old Georges Vermast rode her bike for the … READ MORE

Scientists race to regrow lost knee cartilage

Bad knees sideline athletes and mere mortals alike. About 14 million Americans have osteoarthritis of the knees severe enough to cause pain and inflammation, according to the Arthritis Foundation, and more people are getting the … READ MORE

MS liberation therapy fails the test

Canada has the highest rate of multiple sclerosis in the world. In 2009, Italian physician Paolo Zamboni published an explosive paper about a new treatment for MS, which became known as MS “liberation therapy.” For the … READ MORE

Botox treatment observed less effective for children with CP

More than one injection of botulinum toxin A in children with cerebral palsy (CP) was seen as less effective over the long term and had fewer gait benefits compared to patients injected once or not at all, according to a new … READ MORE

Umbilical cord blood improves motor skills in some children with cerebral palsy

Randomized clinical trial shows improved motor function in children infused with own cells. An infusion of cells from a child’s own umbilical cord blood appears to improve brain connectivity and motor function in children with … READ MORE

Bearspaw boy struggles toward recovery, years after being choked by lanyard

It’s a looming five-year anniversary Kamila Kitzul is loath to ponder. On Dec. 12, 2012, her eight-year-old son Nicholas donned a hall pass dangling from a non-breakaway lanyard for a trip to the boys’ washroom at Bearspaw School, … READ MORE

Major research explores how our bones and muscles age, new ways to block decline

With age, the form and function of our bones and muscles drop off, putting us at increased risk of frailty and falls. Researchers at the Medical College of Georgia at Augusta University are discovering just what happens to the stem … READ MORE

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